Industry 4.0 represents a paradigm shift in manufacturing and production, marked by the convergence of digital technologies, automation, and data-driven insights. HVG portfolio companies are leading the charge in shaping the future of manufacturing by empowering organizations to embrace Industry 4.0 principles and unlock new levels of productivity, efficiency, and flexibility.
Areas of interest include: supply chain optimization, industrial AI, human-AI collaboration, robotics, discrete and continuous manufacturing solutions, operational efficiency, workplace safety.
We look for:
Founder-Product-Market Perfection:
We invest in solutions that solve clear and urgent needs and founders that have deep industry knowledge who understand their customers’ pain points because they have lived them.
Efficiency-Driven Automation:
We focus on companies that are driving efficiency through automation, thereby enhancing productivity, reducing reliance on manual labor, and eliminating waste.
Futureproof Manufacturing:
We back technologies that augment existing manufacturing lines and workers, but can also create new workflows and processes.
Make nuclear cheap enough to safely power the world’s clean energy needs
Aalo Atomics is pioneering the next generation of nuclear energy with factory-fabricated, extra-modular reactors. These reactors, which can be stacked together, are designed to be safe, efficient, and capable of decarbonizing anything from small data centers to cities, aiming to provide affordable, clean energy.
CEO
Matt Loszak
Sectors
Environment
Industrial
Stage
Series A
HQ
Texas
Deal Team
Pete Bastien
Matt Morris
Grace Mathis
The AI-powered industrial surplus markeplace
Amplio’s AI-enabled marketplace enables manufacturers to sell surplus inventory at fair market prices while helping buyers access discounted, essential parts quickly and confidently. This investment aligns perfectly with Hitachi’s commitment to sustainability and efficiency, offering a turnkey solution for managing surplus inventory. Amplio is revolutionizing the supply chain landscape, making it more resilient, transparent, and profitable.
CEO
Trey Closson
Sectors
Environment
Industrial
Stage
Series A
HQ
Georgia
Deal Team
Pete Bastien
Grace Mathis
Matt Morris
Somil Singh
Physical AI: Developer of a Multi-modal Foundation Model that aims to bridge the ‘sensory’ gap
Developer of Newton, a physical AI foundation model designed to provide an unprecedented understanding of the real world. The company offers a multimodal AI foundation model that fuses real-time sensor data with natural language, enabling individuals and organizations to ask open-ended questions about their surroundings and take informed action for improvement.
CEO
Ivan Poupyrev
Sectors
Digital
Industrial
Stage
Seed
HQ
California
Deal Team
Gayathri (G) Radhakrishnan
Galina Sagan
Vamsi Patti
Sustainable closed-loop Battery Recycling returning active battery materials back into the supply chain
Developer of a battery resources technology designed to provide sustainable, closed-loop battery materials systems. The company’s EV battery recycling to commercial-scale production of lithium carbonate, NMC precursor (pCAM), and cathode active materials (CAM), Ascend Elements is revolutionizing the production of sustainable lithium-ion battery materials, enabling clients to have a good return on assets to drive recycling and low-cost battery materials economically.
CEO
Mike O’Kronley
Sectors
Environment
Industrial
Stage
Series D
HQ
Massachusettes
Deal Team
Tobias Jahn
Galina Sagan
Jan Marchewski
Smart building management and tenant engagement platform
Equiem enables real estate owners and operators to create responsive, human-centric working and living environments, by integrating building operation tools, flexible space management and community engagement into one smart building management platform. Manage your property end-to-end with the Equiem One ecosystem, delivering efficiency, experience and intelligence by connecting everyone in a building and across portfolios.
CEO
Gabrielle McMillan
Sectors
Digital
Industrial
Stage
Series B
HQ
Melbourne
Deal Team
Tobias Jahn
AI-powered warehouse automation solution for e-commerce distribution centers and supply chains
Developer of AI-driven warehouse automation with autonomous mobile robots, Goods-to-Person systems, and intelligent software. inVia’s solutions optimize order fulfillment, enhance productivity, and integrate seamlessly with existing infrastructure, providing a scalable and efficient approach to modern warehousing.
CEO
Lior Elazary
Sectors
Industrial
Stage
Series C
HQ
California
Deal Team
Pete Bastien
Pow.Bio’s AI-controlled continuous fermentation technology enables seamless, uninterrupted biomanufacturing, enhancing efficiency and ensuring consistent quality for high-demand bioproducts.
Pow.Bio’s continuous fermentation technology is a game-changer in biomanufacturing. Their advanced bioreactors, combined with AI-controlled software (SOFe), enable seamless, uninterrupted production. This continuous process boosts efficiency, reduces downtime, and ensures consistent quality, making it ideal for producing high-demand bioproducts like organic acids and food proteins.
CEO
Shannon Hall
Sectors
Industrial
Stage
Series A
HQ
Berkeley, CA
Deal Team
Pete Bastien
Matt Morris
Biomanufacturing Platform optimizing Algae to produce high-value compounds in a sustainable way.
Developer of methane reduction technology using Asparagopsis, an algae-based feed additive, to cut livestock methane emissions by up to 95%. Their proprietary Precision Photosynthesis™ process ensures high-quality, sustainable production, making it a game-changer for reducing the environmental impact of cattle farming.
CEO
Nusqe Spanton
Sectors
Environment
Industrial
Stage
Pre-Series A
HQ
Australia
Deal Team
Pete Bastien
The AI operating system for manufacturing and supply chain operations.
Exited
Regrello is building an AI-powered supply chain manager that combines traditional and generative AI to automate end-to-end operational and back-office workflows. Regrello auto generates process diagrams and eliminates manual work, accelerates cycle times, and transforms fragmented processes into intelligent, adaptable systems built for speed, scale, and efficiency.
CEO
Aman Naimat
Sectors
Digital
Industrial
Stage
Series A
HQ
California
Deal Team
Wolfgang Seibold
Jan Marchewski
Pratik Malhotra
Empowering robotics with AI to improve performance and adaptability in manufacturing processes.
Xaba develops new processes and AI-powered software solutions to automate and enable sustainable manufacturing with its xCognition, xTrude and PLCfy platforms. These platforms leverage digital twins of industrial robotic systems, physics AI, language models and multi-modal datasets to enable accurate, repeatable task execution with minimal human oversight delivering cognitive industrial automation and ensuring consistency, robustness, and high-quality execution. Xaba reduces the need for constant human supervision, reprogramming, and waste, improving ROI in manufacturing and construction processes.
CEO
Massimiliano Moruzzi
Sectors
Digital
Industrial
Stage
Seed
HQ
Ontario
Deal Team
Gayathri (G) Radhakrishnan
Vamsi Patti